Stochastic modulation of oscillatory neural activity

Abnormal task modulation of oscillatory neural activity in schizophrenia

Schizophrenia patients have deficits in cognitive function that are a core feature of the disorder. AX-CPT is commonly used to study cognition in schizophrenia, and patients have characteristic pattern of behavioral and ERP response. In AX-CPT subjects respond when a flashed cue "A" is followed by a target "X," ignoring other letter combinations. Patients show reduced hit rate to "go" trials, a...

Onset of oscillatory instabilities under stochastic modulation

We study the effect of external stochastic modulation on a system with O(2) symmetry that exhibits a Hopf or oscillatory instability in the absence of modulation. The study includes a random component in both the control parameter of the bifurcation and in the modulation amplitude. Stability boundaries are computed by either solving the stationary Fokker-Planck equation in the vicinity of the c...

Inferring oscillatory modulation in neural spike trains

Oscillations are observed at various frequency bands in continuous-valued neural recordings like the electroencephalogram (EEG) and local field potential (LFP) in bulk brain matter, and analysis of spike-field coherence reveals that spiking of single neurons often occurs at certain phases of the global oscillation. Oscillatory modulation has been examined in relation to continuous-valued oscill...

Oscillatory activity in excitable neural systems

Stochastic Neural Activity

The activity of a neuron subjected to an input of many small excitatory and inhibitory pulses is analysed. The theoretical model consists of a linear or nonlinear first order system followed by a threshold. Diffusion equations for the transition probability density of the somatic potential are derived. Analytical results for the stationary activity include expressions for the stationary distrib...